benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Base Information

• Chemical Name: benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate
• CAS No.: 1129725-30-9
• Molecular Formula: C₃₅H₃₆ClNO₆
• Molecular Weight: 602.127
• Mol file: 1129725-30-9.mol

Synonyms:benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Chemical Property of benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate

There total 1 articles about benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C27H30ClNO4 (1129725-26-3) + benzyl chloroformate (501-53-1,94274-21-2) → benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate (1129725-30-9)

Guidance literature:

With sodium hydrogencarbonate; In water; ethyl acetate; at 20 ℃;

DOI:10.1002/ejoc.200800796

Reference yield: 82.0%

benzyl (4S,5R,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)-3-chlorotetrahydro-2H-pyran-2-ylcarbamate (1129725-30-9) → benzyl (4R,5S,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylcarbamate (1129725-38-7)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tributyltin chloride; sodium cyanoborohydride; In tert-butyl alcohol; for 2h; Reflux;

DOI:10.1002/ejoc.200800796

upstream raw materials:

C₂₇H₃₀ClNO₄

benzyl chloroformate

Downstream raw materials:

benzyl (4R,5S,6R)-4,5-bis(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-ylcarbamate