[1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine

Base Information

• Chemical Name: [1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine
• CAS No.: 189350-49-0
• Molecular Formula: C₁₆H₁₄F₃N
• Molecular Weight: 277.289
• Mol file: 189350-49-0.mol

Synonyms:[1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine

Chemical Property of [1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine

Chemical Property:

Purity/Quality:

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Technology Process of [1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine

There total 1 articles about [1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-N-[(E)-2,2,2-trifluoro-1-phenylethylidene]-2-phenylethylamine (189350-44-5) → [1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine (189350-49-0) + [1-Phenyl-eth-(E)-ylidene]-((S)-2,2,2-trifluoro-1-phenyl-ethyl)-amine

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; at 19 ℃; for 4h; Product distribution; other chiral Schiff bases, other reagents: triethylamine, 1,4-diazabicyclo<2.2.2>octane, various reactant ratios, other reaction temperature and time;

DOI:10.1021/jo970425c

Reference yield:

[1-Phenyl-eth-(E)-ylidene]-((R)-2,2,2-trifluoro-1-phenyl-ethyl)-amine (189350-49-0) → (R)-(-)-2,2,2-Trifluoro-1-phenylethylamine (22038-85-3)

Guidance literature:

With hydrogenchloride; In diethyl ether; Ambient temperature;

DOI:10.1021/jo970425c

upstream raw materials:

(S)-N-[(E)-2,2,2-trifluoro-1-phenylethylidene]-2-phenylethylamine

Downstream raw materials:

(R)-(-)-2,2,2-Trifluoro-1-phenylethylamine