C₂₀H₂₃FN₂O₃

Base Information

Chemical Name:C₂₀H₂₃FN₂O₃
CAS No.:874440-04-7
Molecular Formula:C₂₀H₂₃FN₂O₃
Molecular Weight:358.413
Hs Code.:

C<sub>20</sub>H<sub>23</sub>FN<sub>2</sub>O<sub>3</sub>

Synonyms:C₂₀H₂₃FN₂O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₂₃FN₂O₃

Chemical Property:

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Technology Process of C₂₀H₂₃FN₂O₃

There total 4 articles about C₂₀H₂₃FN₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18125-46-7
(R)-4-fluorophenylalanine

: 874440-04-7
C₂₀H₂₃FN₂O₃

Guidance literature:: Multi-step reaction with 3 steps

1: Inert atmosphere; Reflux

2: N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere

3: hydrogenchloride / ethyl acetate / 20 °C / Inert atmosphere

With hydrogenchloride; N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm2007062

Reference yield:

: 874336-38-6
C₂₅H₃₁FN₂O₅

: 874440-04-7
C₂₀H₂₃FN₂O₃

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃; Inert atmosphere;
DOI:10.1021/jm2007062

Reference yield:

: 874336-37-5
C₇H₈O₃S*C₁₆H₁₆FNO₂

: 874440-04-7
C₂₀H₂₃FN₂O₃

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere

2: hydrogenchloride / ethyl acetate / 20 °C / Inert atmosphere

With hydrogenchloride; N,N-diethyl-N-isopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 6-chloro-1-hydroxybenzotriazole; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1021/jm2007062