11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin

Base Information

• Chemical Name: 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin
• CAS No.: 167101-19-1
• Molecular Formula: C₃₆H₄₄O₁₅
• Molecular Weight: 716.736
• Mol file: 167101-19-1.mol

Synonyms:11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin

Chemical Property of 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin

There total 3 articles about 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(23S)-3-desacetyl-1-detigloyl-11,20-bis-O-benzyl-22,23-dihydro-23-methoxy-7-oxoazadirachtin (959923-25-2) → 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin (167101-19-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 3h;

DOI:10.1021/ol7027898

Reference yield: 62.0%

11-benzyloxy-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin (167256-58-8) → 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin (167101-19-1)

Guidance literature:

With triethylamine; In methanol; water; at 65 ℃; for 34h;

DOI:10.1016/0040-4020(95)00297-L

Reference yield: 49.0%

C36H44O15 (959923-23-0) → 11-benzyloxy-3-desacetyl-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin (167101-19-1)

Guidance literature:

With Amberlyst 15; 3 A molecular sieve; In methanol; acetonitrile; at 20 ℃;

DOI:10.1002/anie.200703028

upstream raw materials:

11-benzyloxy-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin

(23S)-3-desacetyl-1-detigloyl-11,20-bis-O-benzyl-22,23-dihydro-23-methoxy-7-oxoazadirachtin

C₃₆H₄₄O₁₅

Downstream raw materials:

11-benzyloxy-1-destigloyl-22,23-dihydro-23-β-methoxy-7-oxoazadirachtin