2-(3-Bromo-5-chlorophenyl)acetic acid

Base Information

Chemical Name:2-(3-Bromo-5-chlorophenyl)acetic acid
CAS No.:202001-01-2
Molecular Formula:C₈H₆BrClO₂
Molecular Weight:249.491
Hs Code.:2916399090
European Community (EC) Number:834-128-0
Nikkaji Number:J905.527D

Synonyms:2-(3-BROMO-5-CHLOROPHENYL)ACETIC ACID;202001-01-2;(3-bromo-5-chloro-phenyl)-acetic acid;SCHEMBL137705;KPKHJMMYGGQPKN-UHFFFAOYSA-N;MFCD18373986;AB75452;F85850;EN300-1910978;A854176

Suppliers and Price of 2-(3-Bromo-5-chlorophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-(3-Bromo-5-chlorophenyl)aceticacid
5g
$ 2332.00

AK Scientific
2-(3-Bromo-5-chlorophenyl)aceticacid
250mg
$ 424.00

Total 3 raw suppliers

Chemical Property of 2-(3-Bromo-5-chlorophenyl)acetic acid

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:247.92397
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

2-(3-Bromo-5-chlorophenyl)aceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1Cl)Br)CC(=O)O

Technology Process of 2-(3-Bromo-5-chlorophenyl)acetic acid

There total 3 articles about 2-(3-Bromo-5-chlorophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: ethyl 2-(3-bromo-5-chlorophenyl)-2-cyanoacetate

: 202001-01-2
(3-bromo-5-chloro-phenyl)-acetic acid

Guidance literature:: With sodium hydroxide; at 95 - 100 ℃; for 18h;
DOI:10.1055/s-1997-1385

Reference yield:

: 1056454-88-6
2-(3-bromo-5-chlorophenyl)acetonitrile

: 202001-01-2
(3-bromo-5-chloro-phenyl)-acetic acid

Guidance literature:: With sulfuric acid; acetic acid; In water; Heating / reflux;

Reference yield:

: 33863-76-2
1-bromo-3-chloro-5-fluorobenzene

: 202001-01-2
(3-bromo-5-chloro-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH, NMP / 2.) from 110 deg C to 115 deg C, 30 h

2: 94 percent / aq. NaOH / 18 h / 95 - 100 °C

With 1-methyl-pyrrolidin-2-one; sodium hydroxide; sodium hydride;
DOI:10.1055/s-1997-1385