(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Base Information

Chemical Name:(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine
CAS No.:389621-05-0
Molecular Formula:C₂₂H₂₂N₂O
Molecular Weight:330.429
Hs Code.:

Synonyms:(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Suppliers and Price of (αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

There total 4 articles about (αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 389621-04-9
C₂₂H₂₂N₂O

: 10-phenyl-2-(α-phenylethyl)-1,2,4,5-tetrahydro-1,4-methanopyrrolo[2,1-d][1,2,5]oxadiazepine

: 10-phenyl-2-(α-phenylethyl)-1,2,4,5-tetrahydro-1,4-methanopyrrolo[2,1-d][1,2,5]oxadiazepine

: (αR,3R,3aR,8bR)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

: 389621-05-0
(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Guidance literature:: In toluene; for 24h; Heating;
DOI:10.1016/S0040-4020(01)00785-2

Reference yield:

: 1003-29-8,254729-95-8
2-pyrrole aldehyde

: 389621-05-0
(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / triethylbenzyl ammonium bromide; aq. NaOH / benzene / 1 h / 20 °C

2: 49 percent / MgSO₄ / diethyl ether / 48 h / 20 °C

3: 36 percent / toluene / 24 h / Heating

With sodium hydroxide; triethylbenzyl ammonium bromide; magnesium sulfate; In diethyl ether; toluene; benzene;
DOI:10.1016/S0040-4020(01)00785-2

Reference yield:

: 4392-24-9
Cinnamyl bromide

: 389621-05-0
(αR,3S,3aS,8bS)-3-phenyl-1-(α-phenylethyl)-1,3a,4,8b-tetrahydro-3H-isoxazolo[3,4-a]pyrrolizine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / triethylbenzyl ammonium bromide; aq. NaOH / benzene / 1 h / 20 °C

2: 49 percent / MgSO₄ / diethyl ether / 48 h / 20 °C

3: 36 percent / toluene / 24 h / Heating

With sodium hydroxide; triethylbenzyl ammonium bromide; magnesium sulfate; In diethyl ether; toluene; benzene;
DOI:10.1016/S0040-4020(01)00785-2