2-benzyl-3-phenyl-2-trimethylsilyloxypropanal

Base Information

• Chemical Name: 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal
• CAS No.: 932746-99-1
• Molecular Formula: C₁₉H₂₄O₂Si
• Molecular Weight: 312.484
• Mol file: 932746-99-1.mol

Synonyms:2-benzyl-3-phenyl-2-trimethylsilyloxypropanal

Chemical Property of 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal

There total 2 articles about 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyl-3-phenyl-2-((trimethylsilyl)oxy)propanenitrile → 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal (932746-99-1)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 1h;

DOI:10.1021/ja063051q

Reference yield:

1,3-Diphenylpropanone (102-04-5) → 2-benzyl-3-phenyl-2-trimethylsilyloxypropanal (932746-99-1)

Guidance literature:

Multi-step reaction with 2 steps

1: I₂ / CH₂Cl₂ / 0.5 h / 0 °C

2: 2.97 g / DIBAH / CH₂Cl₂; toluene / 1 h / -78 °C

With iodine; diisobutylaluminium hydride; In dichloromethane; toluene;

DOI:10.1021/ja063051q

Reference yield:

2-benzyl-3-phenyl-2-trimethylsilyloxypropanal (932746-99-1) → 1,4-diphenyl-3-trimethylsiloxy-2-butanone + 1,4-diphenyl-3-trimethylsiloxy-2-butanone

Guidance literature:

chiral organoaluminum Lewis acid catalyst; In toluene; at -20 ℃; for 12h; Title compound not separated from byproducts;

DOI:10.1021/ja063051q

upstream raw materials:

1,3-Diphenylpropanone