Technology Process of 1,1-di-(p-bromophenylethyl)epoxyethane
There total 3 articles about 1,1-di-(p-bromophenylethyl)epoxyethane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
trimethylsulfoxonium iodide;
With
sodium hydride;
In
dimethyl sulfoxide; mineral oil;
at 0 - 20 ℃;
for 0.5h;
Inert atmosphere;
1,5-Di-(4-bromophenyl)-3-pentanone;
In
dimethyl sulfoxide; mineral oil;
for 4.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium hydroxide; water / ethanol / 20 °C
2.1: hydrogen; acetic acid / 5%-palladium/activated carbon / ethyl acetate / 2.5 h / 3000.3 Torr / Autoclave
2.2: 0 - 20 °C
3.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere
3.2: 4.5 h
With
water; hydrogen; sodium hydride; acetic acid; potassium hydroxide;
5%-palladium/activated carbon;
In
ethanol; dimethyl sulfoxide; ethyl acetate; mineral oil;
1.1: Aldol Condensation;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogen; acetic acid / 5%-palladium/activated carbon / ethyl acetate / 2.5 h / 3000.3 Torr / Autoclave
1.2: 0 - 20 °C
2.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere
2.2: 4.5 h
With
hydrogen; sodium hydride; acetic acid;
5%-palladium/activated carbon;
In
dimethyl sulfoxide; ethyl acetate; mineral oil;
