(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

Base Information

Chemical Name:(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane
CAS No.:1292810-72-0
Molecular Formula:C₂₃H₃₈O₅Si
Molecular Weight:422.637
Hs Code.:

Synonyms:(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

Suppliers and Price of (1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

There total 1 articles about (1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 918955-50-7
C₁₅H₃₀O₄Si

: 824-94-2
p-methoxybenzyl chloride

: 1292810-72-0
(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

Guidance literature:: C₁₅H₃₀O₄Si; With sodium hexamethyldisilazane; In tetrahydrofuran; for 0.166667h; Inert atmosphere;

p-methoxybenzyl chloride; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1021/ml2000356

Reference yield: 97.0%

: 1292810-72-0
(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

: 1292810-73-1
(1R,4R,5S,6R)-6-(4-methoxybenzyloxy)-4-hydroxy-2,8-dioxa-bicyclo[3.3.0]octane

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
DOI:10.1021/ml2000356

Reference yield:

: 1292810-72-0
(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-4-tiisopropylsilanoxy-2,8-dioxa-bicyclo[3.3.0]octane

: 1292810-80-0
C₂₁H₂₃FO₅

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C / Inert atmosphere

2.2: 3 h / 0 - 20 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran; mineral oil;
DOI:10.1021/ml2000356