C₄₅H₇₂O₁₁SSi

Base Information

Chemical Name:C₄₅H₇₂O₁₁SSi
CAS No.:954106-49-1
Molecular Formula:C₄₅H₇₂O₁₁SSi
Molecular Weight:849.212
Hs Code.:

C<sub>45</sub>H<sub>72</sub>O<sub>11</sub>SSi

Synonyms:C₄₅H₇₂O₁₁SSi

Suppliers and Price of C₄₅H₇₂O₁₁SSi

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₅H₇₂O₁₁SSi

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of C₄₅H₇₂O₁₁SSi

There total 23 articles about C₄₅H₇₂O₁₁SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 954106-39-9
C₂₅H₃₁NO₄

: 954106-49-1
C₄₅H₇₂O₁₁SSi

Guidance literature:: Multi-step reaction with 16 steps

1.1: NaHDMS / tetrahydrofuran / 2 h / -78 °C

1.2: 80 percent / tetrahydrofuran / -78 - -20 °C

2.1: 92 percent / LiOH*H₂O; aq. H₂O₂ / tetrahydrofuran / 2 h / 20 °C

3.1: 96 percent / H₂; K₂CO₃ / Pd/C / methanol / 0.83 h

4.1: EDC; DMAP / dimethylformamide / 12 h / 50 °C

5.1: ((S)-1-Ph-2-piperidin-1-yl-Et)-(2,2,2-triF-Et)amine; n-BuLi / tetrahydrofuran; hexane / 1 h

5.2: Me₃SiCl / 0.58 h / -78 - 0 °C

6.1: 0.310 g / LiAlH₄ / tetrahydrofuran / 5 h / Heating

7.1: n-Bu₂SnO / toluene / 0.75 h / Heating

7.2: 71 percent / CH₂Cl₂ / 1 h / 0 °C

8.1: imidazole / dimethylformamide / 3 h / 65 °C

8.2: dimethylformamide / 20 h / 80 °C

9.1: 0.174 g / DDQ / CH₂Cl₂; H₂O / 1.5 h / 20 °C

10.1: O₃; N-methylmorpholine N-oxide; benzyl ethyl eter / CH₂Cl₂ / 0.13 h / -78 °C

10.2: 80 percent / NaBH₄ / methanol / 1 h / -40 - -10 °C

11.1: DMSO; (COCl)2; Et₃N / CH₂Cl₂ / 1.67 h / -78 - 0 °C

12.1: 0.112 g / Bn₂NH*CF₃COOH / toluene / 16 h / 45 °C

13.1: NaBH₄ / ethanol / 1 h / -78 - 0 °C

13.2: aq. HF; pyridine / tetrahydrofuran / 9 h / 20 °C

13.3: 81 percent / i-Pr₂NEt; tetra-n-butylammonium iodide / CH₂Cl₂ / 10 h / 50 °C

14.1: 78 percent / EtOH / Raney Ni W-2 / 7 h

15.1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

15.2: 11 mg / DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

With 1H-imidazole; dmap; lithium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; ethanol; hydrogen; dihydrogen peroxide; sodium hexamethyldisilazane; di(n-butyl)tin oxide; potassium carbonate; ozone; dimethyl sulfoxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 4-methylmorpholine N-oxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium on activated charcoal; Raney Ni W-2; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 5.1: Ireland-Claisen rearrngement / 11.1: Swern oxidation reaction;
DOI:10.1016/j.tetlet.2007.07.182

Reference yield:

: 954106-24-2
C₂₇H₃₈O₅

: 954106-49-1
C₄₅H₇₂O₁₁SSi

Guidance literature:: Multi-step reaction with 13 steps

1.1: EDC; DMAP / dimethylformamide / 12 h / 50 °C

2.1: ((S)-1-Ph-2-piperidin-1-yl-Et)-(2,2,2-triF-Et)amine; n-BuLi / tetrahydrofuran; hexane / 1 h

2.2: Me₃SiCl / 0.58 h / -78 - 0 °C

3.1: 0.310 g / LiAlH₄ / tetrahydrofuran / 5 h / Heating

4.1: n-Bu₂SnO / toluene / 0.75 h / Heating

4.2: 71 percent / CH₂Cl₂ / 1 h / 0 °C

5.1: imidazole / dimethylformamide / 3 h / 65 °C

5.2: dimethylformamide / 20 h / 80 °C

6.1: 0.174 g / DDQ / CH₂Cl₂; H₂O / 1.5 h / 20 °C

7.1: O₃; N-methylmorpholine N-oxide; benzyl ethyl eter / CH₂Cl₂ / 0.13 h / -78 °C

7.2: 80 percent / NaBH₄ / methanol / 1 h / -40 - -10 °C

8.1: DMSO; (COCl)2; Et₃N / CH₂Cl₂ / 1.67 h / -78 - 0 °C

9.1: 0.112 g / Bn₂NH*CF₃COOH / toluene / 16 h / 45 °C

10.1: NaBH₄ / ethanol / 1 h / -78 - 0 °C

10.2: aq. HF; pyridine / tetrahydrofuran / 9 h / 20 °C

10.3: 81 percent / i-Pr₂NEt; tetra-n-butylammonium iodide / CH₂Cl₂ / 10 h / 50 °C

11.1: 78 percent / EtOH / Raney Ni W-2 / 7 h

12.1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

12.2: 11 mg / DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; ethanol; di(n-butyl)tin oxide; ozone; dimethyl sulfoxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 4-methylmorpholine N-oxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; Raney Ni W-2; In tetrahydrofuran; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 2.1: Ireland-Claisen rearrngement / 8.1: Swern oxidation reaction;
DOI:10.1016/j.tetlet.2007.07.182

Reference yield:

: 954106-09-3
C₃₁H₅₄O₆Si₂

: 954106-49-1
C₄₅H₇₂O₁₁SSi

Guidance literature:: Multi-step reaction with 15 steps

1.1: DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

1.2: 88 percent / DMSO; (COCl)2; Et₃N / CH₂Cl₂ / 0.83 h / -78 - 0 °C

2.1: (S)-2-piperidino-1,1,2-triphenylethanol / hexane; toluene / 48 h / -20 °C

3.1: EDC; DMAP / dimethylformamide / 12 h / 50 °C

4.1: ((S)-1-Ph-2-piperidin-1-yl-Et)-(2,2,2-triF-Et)amine; n-BuLi / tetrahydrofuran; hexane / 1 h

4.2: Me₃SiCl / 0.58 h / -78 - 0 °C

5.1: 0.310 g / LiAlH₄ / tetrahydrofuran / 5 h / Heating

6.1: n-Bu₂SnO / toluene / 0.75 h / Heating

6.2: 71 percent / CH₂Cl₂ / 1 h / 0 °C

7.1: imidazole / dimethylformamide / 3 h / 65 °C

7.2: dimethylformamide / 20 h / 80 °C

8.1: 0.174 g / DDQ / CH₂Cl₂; H₂O / 1.5 h / 20 °C

9.1: O₃; N-methylmorpholine N-oxide; benzyl ethyl eter / CH₂Cl₂ / 0.13 h / -78 °C

9.2: 80 percent / NaBH₄ / methanol / 1 h / -40 - -10 °C

10.1: DMSO; (COCl)2; Et₃N / CH₂Cl₂ / 1.67 h / -78 - 0 °C

11.1: 0.112 g / Bn₂NH*CF₃COOH / toluene / 16 h / 45 °C

12.1: NaBH₄ / ethanol / 1 h / -78 - 0 °C

12.2: aq. HF; pyridine / tetrahydrofuran / 9 h / 20 °C

12.3: 81 percent / i-Pr₂NEt; tetra-n-butylammonium iodide / CH₂Cl₂ / 10 h / 50 °C

13.1: 78 percent / EtOH / Raney Ni W-2 / 7 h

14.1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

14.2: 11 mg / DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; ethanol; diisobutylaluminium hydride; di(n-butyl)tin oxide; ozone; dimethyl sulfoxide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; 4-methylmorpholine N-oxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; Raney Ni W-2; In tetrahydrofuran; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 1.2: Swern oxidation / 4.1: Ireland-Claisen rearrngement / 10.1: Swern oxidation reaction;
DOI:10.1016/j.tetlet.2007.07.182