Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)

Base Information

Chemical Name:Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)
CAS No.:22049-65-6
Molecular Formula:C₈H₁₂N₂O₂
Molecular Weight:168.195
Hs Code.:
Mol file:22049-65-6.mol

Synonyms:Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)

Suppliers and Price of Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI)

There total 6 articles about Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-2-methyl- (8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 865879-23-8
8a-benzyloxycarbonyl-2-methyl-1,4-dioxo-hexahydropyrrolo[1,2-a]pyrazine

: 5616-94-4,22049-65-6
2-methyl-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol / 1 h

2: 197 mg / toluene / 24 h / Heating

With hydrogen; palladium on activated charcoal; In methanol; toluene;
DOI:10.1016/j.tet.2005.06.084

Reference yield:

: 2-(2-methylamino-acetylamino)-malonic acid dibenzyl ester

: 5616-94-4,22049-65-6
2-methyl-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 4.59 g / toluene / 24 h / Heating

2: 69 percent / NaH / dimethylformamide / 24 h / 0 °C

3: H₂ / Pd/C / methanol / 1 h

4: 197 mg / toluene / 24 h / Heating

With hydrogen; sodium hydride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.tet.2005.06.084

Reference yield:

: 519141-03-8
1-methyl-3-benzyloxycarbonylpiperazine-2,5-dione

: 5616-94-4,22049-65-6
2-methyl-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / NaH / dimethylformamide / 24 h / 0 °C

2: H₂ / Pd/C / methanol / 1 h

3: 197 mg / toluene / 24 h / Heating

With hydrogen; sodium hydride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.tet.2005.06.084