2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide

Base Information

• Chemical Name: 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide
• CAS No.: 155580-14-6
• Molecular Formula: C₄₀H₄₅NO₁₀
• Molecular Weight: 699.798
• Mol file: 155580-14-6.mol

Synonyms:2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide

Chemical Property of 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide

There total 5 articles about 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(2-Hydroxy-5-methylphenyl)-2,2'-bis<2-<2-<2-(phenylmethoxy)ethoxy>ethoxy>ethoxy>-<1,1'-binaphthalene>-3-carboxamide (155580-12-4) → 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide (155580-14-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; ethyl acetate;

DOI:10.1002/recl.19931121106

Reference yield:

triethylene glycol monobenzyl ether (55489-58-2,1201808-31-2) → 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide (155580-14-6)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine

2: 85 percent / K₂CO₃ / acetonitrile / Heating

3: 100 percent / aq. KOH / methanol / 1 h / Heating

4: 1.) HOBT*H₂O, DCC / 1.) CH₂Cl₂, r.t., 1 h, 2.) overnight

5: 100 percent / H₂ / 10percent Pd-C / ethyl acetate; ethanol

With pyridine; potassium hydroxide; hydrogen; potassium carbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; ethyl acetate; acetonitrile;

DOI:10.1002/recl.19931121106

Reference yield:

(aS)-methyl 2,2'-dihydroxy-1,1'-binaphthalene-3-carboxylate (128702-23-8,145415-62-9,145415-63-0) → 2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide (155580-14-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / K₂CO₃ / acetonitrile / Heating

2: 100 percent / aq. KOH / methanol / 1 h / Heating

3: 1.) HOBT*H₂O, DCC / 1.) CH₂Cl₂, r.t., 1 h, 2.) overnight

4: 100 percent / H₂ / 10percent Pd-C / ethyl acetate; ethanol

With potassium hydroxide; hydrogen; potassium carbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; ethyl acetate; acetonitrile;

DOI:10.1002/recl.19931121106

upstream raw materials:

N-(2-Hydroxy-5-methylphenyl)-2,2'-bis<2-<2-<2-(phenylmethoxy)ethoxy>ethoxy>ethoxy>-<1,1'-binaphthalene>-3-carboxamide

triethylene glycol monobenzyl ether

(aS)-methyl 2,2'-dihydroxy-1,1'-binaphthalene-3-carboxylate

2,2'-Bis<2-<2-<2-(phenylmethoxy)ethoxy>ethoxy>ethoxy>-<1,1'-binaphthalene>-3-carboxylic acid

Downstream raw materials:

2,2'-Bis<2-<2-<2-<3-formyl-2-hydroxyphenoxy>ethoxy>ethoxy>ethoxy>-N-(2-hydroxy-5-methylphenyl)-<1,1'-binaphthalene>-3-carboxamide

2,2'-Bis<2-<2-<2-<<(4-methylphenyl)sulfonyl>oxy>ethoxy>ethoxy>ethoxy>-N-<5-methyl-2-(2-propenyloxy)phenyl>-<1,1'-binaphthalene>-3-carboxamide

2,2'-Bis<2-<2-<2-<3-formyl-2-(2-propenyloxy)phenoxy>ethoxy>ethoxy>ethoxy>-N-<5-methyl-2-(2-propenyloxy)phenyl>-<1,1'-binaphthalene>-3-carboxamide

2,2'-Bis<2-<2-(2-hydroxyethoxy)ethoxy>ethoxy>-N-<5-methyl-2-(2-propenyloxy)phenyl>-<1,1'-binaphthalene>-3-carboxamide