Technology Process of C27H28N4O6S2
There total 8 articles about C27H28N4O6S2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C13H10BrNO4; (S)-2-(3-t-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl)-1,3-thiazole-4-thiocarboxamide;
With
potassium hydrogencarbonate;
In
1,2-dimethoxyethane;
at 20 ℃;
Inert atmosphere;
With
pyridine; trifluoroacetic anhydride;
In
1,2-dimethoxyethane;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
With
triethylamine;
In
1,2-dimethoxyethane;
at 20 ℃;
for 0.333333h;
Inert atmosphere;
DOI:10.1021/ol401412v
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonium hydroxide / methanol / Inert atmosphere
2.1: Lawessons reagent / benzene / 16 h / Inert atmosphere; Reflux
3.1: potassium hydrogencarbonate / 1,2-dimethoxyethane / 20 °C / Inert atmosphere
3.2: 3 h / 0 - 20 °C / Inert atmosphere
3.3: 0.33 h / 20 °C / Inert atmosphere
With
Lawessons reagent; ammonium hydroxide; potassium hydrogencarbonate;
In
methanol; 1,2-dimethoxyethane; benzene;
3.1: |Hantzsch Thiazole Synthesis / 3.2: |Hantzsch Thiazole Synthesis / 3.3: |Hantzsch Thiazole Synthesis;
DOI:10.1021/ol401412v
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: ammonium hydroxide / methanol / 12 h / Inert atmosphere
2.1: Lawessons reagent / tetrahydrofuran / 16 h / Inert atmosphere; Reflux
3.1: potassium hydrogencarbonate / 1,2-dimethoxyethane / 20 °C / Inert atmosphere
3.2: 3 h / 0 - 20 °C / Inert atmosphere
3.3: 1 h / 20 °C / Inert atmosphere
4.1: ammonium hydroxide / methanol / Inert atmosphere
5.1: Lawessons reagent / benzene / 16 h / Inert atmosphere; Reflux
6.1: potassium hydrogencarbonate / 1,2-dimethoxyethane / 20 °C / Inert atmosphere
6.2: 3 h / 0 - 20 °C / Inert atmosphere
6.3: 0.33 h / 20 °C / Inert atmosphere
With
Lawessons reagent; ammonium hydroxide; potassium hydrogencarbonate;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; benzene;
3.1: |Hantzsch Thiazole Synthesis / 3.2: |Hantzsch Thiazole Synthesis / 3.3: |Hantzsch Thiazole Synthesis / 6.1: |Hantzsch Thiazole Synthesis / 6.2: |Hantzsch Thiazole Synthesis / 6.3: |Hantzsch Thiazole Synthesis;
DOI:10.1021/ol401412v
