(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

Base Information

Chemical Name:(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide
CAS No.:385435-05-2
Molecular Formula:C₂₀H₃₀ClNO₂SSi
Molecular Weight:412.068
Hs Code.:

Synonyms:(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

Suppliers and Price of (S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

There total 1 articles about (S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 587-04-2
m-Chlorobenzaldehyde

: 253665-34-8
(1S,2R,4R,S_S)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptane-1-methanesulfinamide

: 385435-05-2
(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

Guidance literature:: With titanium(IV) tetraethanolate; at 20 ℃;
DOI:10.1016/S0040-4020(01)00833-X

Reference yield:

: 57592-45-7
ethyl (E)-3-ethoxy-2-butenoate

: 385435-05-2
(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

: 6-(3-chloro-phenyl)-4-ethoxy-5,6-dihydro-1H-pyridin-2-one

: 6-(3-chloro-phenyl)-4-ethoxy-5,6-dihydro-1H-pyridin-2-one

Guidance literature:: ethyl (E)-3-ethoxy-2-butenoate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -70 ℃; for 2.5h;

(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide; In tetrahydrofuran; hexane; at -30 ℃; for 3.5h;

With hydrogenchloride; In ethanol; dichloromethane; at 20 ℃; for 24h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00833-X

Reference yield:

: 130573-43-2
(2,2-dimethyl-6-methylene-6H-1,3-dioxin-4-yloxy)trimethylsilane

: 385435-05-2
(S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide

: 6-(3-chlorophenyl)piperidine-2,4-dione

: 6-(3-chlorophenyl)piperidine-2,4-dione

Guidance literature:: (2,2-dimethyl-6-methylene-6H-1,3-dioxin-4-yloxy)trimethylsilane; (S)-N-(3-chlorophenylmethylidene)-1-[(1S,2R,4R)-7,7-dimethyl-2-(trimethylsilyloxy)bicyclo[2.2.1]heptan-1-yl]methanesulfinamide; With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -70 ℃; for 3h;

With water; at -70 - 20 ℃;

With potassium carbonate; In methanol; at 20 ℃; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00833-X