N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

Base Information

Chemical Name:N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride
CAS No.:1242245-99-3
Molecular Formula:C₂₂H₁₇ClN₄O*ClH
Molecular Weight:425.317
Hs Code.:

Synonyms:N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

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Chemical Property of N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

Chemical Property:

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Technology Process of N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

There total 2 articles about N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1242146-38-8
ethyl (1E)-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)acetimidate

: 106-47-8
4-chloro-aniline

: 1242245-99-3
N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

Guidance literature:: ethyl (1E)-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)acetimidate; 4-chloro-aniline; With acetic acid; Reflux;

With hydrogenchloride; In methanol;
DOI:10.1016/j.cclet.2010.04.009

Reference yield:

: 1904-60-5
3-amino-2-phenylquinazolin-4(3H)-one

: 1242245-99-3
N'-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-N-(4-chlorophenyl)acetamidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 5 h / Reflux

2: acetic acid / Reflux

With acetic acid;
DOI:10.1016/j.cclet.2010.04.009