2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose

Base Information

• Chemical Name: 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose
• CAS No.: 904690-07-9
• Molecular Formula: C₄₈H₅₆O₂₆
• Molecular Weight: 1048.96
• Mol file: 904690-07-9.mol

Synonyms:2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose

Chemical Property of 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose

There total 3 articles about 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

allyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranoside (1117751-18-4) → 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose (904690-07-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; acetic acid; at 80 ℃; for 1h;

DOI:10.1016/j.bmc.2008.11.004

Reference yield:

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl trichloroimidate (121238-27-5) → 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose (904690-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / 0 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; acetic acid / 1 h / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; trimethylsilyl trifluoromethanesulfonate; acetic acid; In dichloromethane;

DOI:10.1016/j.bmc.2008.11.004

Reference yield:

allyl 2,4-di-O-benzoyl-α-D-mannopyranoside (314038-22-7) → 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranose (904690-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / 0 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; acetic acid / 1 h / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; trimethylsilyl trifluoromethanesulfonate; acetic acid; In dichloromethane;

DOI:10.1016/j.bmc.2008.11.004

upstream raw materials:

allyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl]-(1->6)-2,4-di-O-benzoyl-α-D-mannopyranoside

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl trichloroimidate

allyl 2,4-di-O-benzoyl-α-D-mannopyranoside

Downstream raw materials:

C₅₁H₆₃NO₂₆

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-[2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->6)-]-2,4-di-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate