8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene

Base Information

• Chemical Name: 8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene
• CAS No.: 447454-15-1
• Molecular Formula: C₁₈H₂₀F₅NO₂
• Molecular Weight: 377.354
• Mol file: 447454-15-1.mol

Synonyms:8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene

Chemical Property of 8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene

There total 1 articles about 8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2,3,4,5,6-pentafluoroaniline (771-60-8) + (2E,6E)-3,7-dimethyl-8-oxoocta-2,6-dien-1-yl acetate (37905-02-5) → 8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene (447454-15-1)

Guidance literature:

2,3,4,5,6-pentafluoroaniline; With pyridine; titanium tetrachloride; In dichloromethane; toluene; at 20 ℃; for 0.0833333h;

(2E,6E)-3,7-dimethyl-8-oxoocta-2,6-dien-1-yl acetate; In dichloromethane; toluene; at 20 ℃; for 8h;

With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; toluene; at 20 ℃; Further stages.;

DOI:10.1021/ja0124717

Reference yield: 96.0%

8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene (447454-15-1) → 8-(pentafluoroaniline)-3,7-dimethyl-2,6-octadien-1-ol (447454-19-5)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃;

DOI:10.1021/ja0124717

Reference yield:

8-(pentafluoroaniline)-3,7-dimethyl-1-acetoxyl-2,6-octadiene (447454-15-1) → 8-(pentafluoroaniline)-3,7-dimethyl-1-chloro-2,6-octadiene (447454-22-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / aq. potassium carbonate / methanol / 20 °C

2: 83 percent / N,N-diisopropylethylamine; dichlorotriphenylphosphorane / acetonitrile / 0.67 h / 0 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; dichlorotriphenylphosphorane; In methanol; acetonitrile;

DOI:10.1021/ja0124717

upstream raw materials:

2,3,4,5,6-pentafluoroaniline

(2E,6E)-3,7-dimethyl-8-oxoocta-2,6-dien-1-yl acetate

Downstream raw materials:

8-(pentafluoroaniline)-3,7-dimethyl-2,6-octadien-1-ol

8-(pentafluoroaniline)-3,7-dimethyl-1-chloro-2,6-octadiene