9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine

Base Information

• Chemical Name: 9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine
• CAS No.: 1220626-28-7
• Molecular Formula: C₂₂H₂₂FN₅O₆
• Molecular Weight: 471.445
• Mol file: 1220626-28-7.mol

Synonyms:9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine

Chemical Property of 9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine

There total 1 articles about 9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

9-(2,4-di-O-acetyl-3,6-di-deoxy-3-fluoro-6-iodo-β-D-glucopyranosyl)-N6-benzoyladenine (1220626-22-1) → 9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine (1220626-28-7)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; triethylamine; In ethanol; ethyl acetate; at 20 ℃; for 24h;

DOI:10.1016/j.bioorg.2009.11.001

Reference yield: 53.0%

9-(2,4-di-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine (1220626-28-7) → 9-(4-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine (1220626-37-8)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; sodium acetate; at 20 ℃; for 12h; regioselective reaction;

DOI:10.1016/j.bioorg.2009.11.001

upstream raw materials:

9-(2,4-di-O-acetyl-3,6-di-deoxy-3-fluoro-6-iodo-β-D-glucopyranosyl)-N6-benzoyladenine

Downstream raw materials:

9-(4-O-acetyl-3,6-dideoxy-3-fluoro-β-D-glucopyranosyl)-N6-benzoyladenine