2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

Base Information

Chemical Name:2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester
CAS No.:1155261-31-6
Molecular Formula:C₃₀H₂₈N₂O₄
Molecular Weight:480.563
Hs Code.:

Synonyms:2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

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Chemical Property of 2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

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Technology Process of 2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

There total 1 articles about 2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 118-48-9
isatoic anhydride

: 1155261-22-5
O-benzyl-DL-tyrosine benzyl ester hydrochloride

: 1155261-31-6
2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

Guidance literature:: With triethylamine; In ethyl acetate; for 4h; Reflux;
DOI:10.1016/j.bmc.2009.02.012

Reference yield: 26.0%

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 1155261-31-6
2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester

: (2RS)-3-(4-benzyloxyphenyl)-2-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}propionic acid benzyl ester

Guidance literature:: Indole-2-carboxylic acid; With phosphorus pentachloride; acetyl chloride; at 20 ℃; for 3.5h; Cooling with ice;

2-(RS)-(2-aminobenzoylamino)-3-(4-benzyloxyphenyl)propionic acid benzyl ester; With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2009.02.012