8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol

Base Information

Chemical Name:8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol
CAS No.:21598-02-7
Molecular Formula:C₁₇H₁₉ClN₂O₂S
Molecular Weight:350.869
Hs Code.:
DSSTox Substance ID:DTXSID90175958
Nikkaji Number:J336.521B
Wikidata:Q27216162
ChEMBL ID:CHEMBL301785
Mol file:21598-02-7.mol

Synonyms:7,8-DHCPZ;7,8-dihydroxychlorpromazine;7,8-dihydroxychlorpromazine monohydrochloride;7,8-DIOH CPZ

Suppliers and Price of 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol

Chemical Property:

Vapor Pressure:2.47E-13mmHg at 25°C
Refractive Index:1.665
Boiling Point:564.2°Cat760mmHg
PKA:8.98±0.20(Predicted)
Flash Point:295°C
PSA：72.24000
Density:1.35g/cm³
LogP:4.37060
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:350.0855767
Heavy Atom Count:23
Complexity:401

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=CC(=C(C=C2SC3=C1C=C(C=C3)Cl)O)O

Technology Process of 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol

There total 2 articles about 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazine-2,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-chloro-2-iodo-phenylsulfanyl)-4,5-bis-methoxymethoxy-aniline

: 21598-02-7
7,8-Dihydroxy chlorpromazin

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / Cu / dimethylformamide / Heating

2: (i) NaH, DMSO, (ii) /BRN= 605294/, (iii) HCl, MeOH

With potassium carbonate; copper; In N,N-dimethyl-formamide;