(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

Base Information

Chemical Name:(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine
CAS No.:1620231-38-0
Molecular Formula:C₁₈H₁₇F₂N₃O
Molecular Weight:329.349
Hs Code.:

Synonyms:(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

Chemical Property:

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Technology Process of (S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

There total 3 articles about (S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620231-37-9
(R)-N-((S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethyl)-2-methylpropane-2-sulfinamide

: 1620231-38-0
(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; for 3h;

Reference yield:

: 5709-65-9
1-(4-methoxyphenyl)-1H-imidazole-2-carbaldehyde

: 1620231-38-0
(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: copper(II) sulfate / dichloromethane / 15 h / 20 °C

2: tetrahydrofuran; diethyl ether / 2 h / -78 °C

3: hydrogenchloride / dichloromethane; 1,4-dioxane / 3 h

With hydrogenchloride; copper(II) sulfate; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane;

Reference yield:

: 1620231-35-7
(R)-N-((1-(4-methoxyphenyl)-1H-imidazol-2-yl)methylene)-2-methylpropane-2-sulfinamide

: 1620231-38-0
(S)-2-(3,5-difluorophenyl)-1-(1-(4-methoxyphenyl)-1H-imidazol-2-yl)ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 2 h / -78 °C

2: hydrogenchloride / dichloromethane; 1,4-dioxane / 3 h

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane;