(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride

Base Information

Chemical Name:(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride
CAS No.:108704-93-4
Molecular Formula:C₁₀H₉ClO₃
Molecular Weight:212.633
Hs Code.:
European Community (EC) Number:822-410-6

Synonyms:108704-93-4;(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride;2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetyl chloride;2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetyl chloride;starbld0032523;SCHEMBL9789917;AKOS000302278;EN300-234754;F1908-0053

Suppliers and Price of (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)acetylChloride
250mg
$ 285.00

TRC
2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)acetylChloride
25mg
$ 45.00

Matrix Scientific
(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride
1g
$ 378.00

American Custom Chemicals Corporation
(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-ACETYL CHLORIDE 95.00%
500MG
$ 796.95

Total 2 raw suppliers

Chemical Property of (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:212.0240218
Heavy Atom Count:14
Complexity:219

Purity/Quality:

98%min ^*data from raw suppliers

2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)acetylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC2=C(O1)C=CC(=C2)CC(=O)Cl

Technology Process of (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride

There total 1 articles about (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17253-11-1
2,3-dihydro-1,4-benzodioxin-6-ylacetic acid

: 108704-93-4
2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetyl chloride

Guidance literature:: With thionyl chloride; In dichloromethane; for 1h; Heating;
DOI:10.1021/jm00167a033

Reference yield:

: 108704-93-4
2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetyl chloride

: 125846-54-0
8-(3-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amino}-propyl)-2,3,6,8,9,10-hexahydro-1,4-dioxa-8-aza-cyclohepta[b]naphthalen-7-one

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / CH₂Cl₂ / 1 h / Ambient temperature

2: glacial acetic acid, conc. HCl / 17 h / Ambient temperature

3: 1.) potassium tert-butoxide / 1.) DMSO, RT, 30 min, 2.) RT, 30 min

4: 2 h / 90 - 95 °C

5: H₂ / Pd/C / acetic acid / 10 h / 3750.3 Torr / Ambient temperature

With hydrogenchloride; potassium tert-butylate; hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In dichloromethane; acetic acid;
DOI:10.1021/jm00167a033

Reference yield:

: 108704-93-4
2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetyl chloride

: 8-(3-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amino}-propyl)-2,3,6,8-tetrahydro-1,4-dioxa-8-aza-cyclohepta[b]naphthalen-7-one

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / CH₂Cl₂ / 1 h / Ambient temperature

2: glacial acetic acid, conc. HCl / 17 h / Ambient temperature

3: 1.) potassium tert-butoxide / 1.) DMSO, RT, 30 min, 2.) RT, 30 min

4: 2 h / 90 - 95 °C

With hydrogenchloride; potassium tert-butylate; acetic acid; triethylamine; In dichloromethane;
DOI:10.1021/jm00167a033