(Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate

Base Information

• Chemical Name: (Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate
• CAS No.: 1334313-63-1
• Molecular Formula: C₂₁H₂₆N₂O₄S
• Molecular Weight: 402.514
• Mol file: 1334313-63-1.mol

Synonyms:(Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate

Chemical Property of (Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate

There total 1 articles about (Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,4,6-trimethylbenzenesulfonohydrazide (16182-15-3) + 2-oxo-4-phenylbutanoic acid ethyl ester (64920-29-2) → (Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate (1334313-63-1)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 ℃;

DOI:10.1002/chem.201101590

Reference yield: 37.0%

(Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate (1334313-63-1) → ethyl 2-diazo-4-phenylbutanoate (82830-86-2)

Guidance literature:

With triethylamine; In dichloromethane; at 80 ℃; under 12929 Torr;

DOI:10.1002/chem.201101590

Reference yield:

(Z)-ethyl 2-(2-mesitylsulfonylhydrazono)-4-phenylbutanoate (1334313-63-1) → ethyl 2-isobutoxy-4-phenylbutanoate (1334313-85-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 80 °C / 12929 Torr

2: rhodium (II) octanoate dimer / dichloromethane

With rhodium (II) octanoate dimer; triethylamine; In dichloromethane; 1: Bamford-Stevens reaction;

DOI:10.1002/chem.201101590

upstream raw materials:

2,4,6-trimethylbenzenesulfonohydrazide

2-oxo-4-phenylbutanoic acid ethyl ester

Downstream raw materials:

ethyl 2-diazo-4-phenylbutanoate

ethyl 2-isobutoxy-4-phenylbutanoate

ethyl 2-((4-methoxyphenyl)amino)-4-phenylbutanoate