Technology Process of (Z)-6-(p-tolyl)hex-3-en-1-ol
There total 3 articles about (Z)-6-(p-tolyl)hex-3-en-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; nickel(II) acetate tetrahydrate; ethylenediamine;
In
ethanol;
at 20 ℃;
for 4h;
stereoselective reaction;
Inert atmosphere;
DOI:10.1021/jo201027u
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium amide; ferric nitrate / diethyl ether / 1 h / -78 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: sodium tetrahydroborate; nickel(II) acetate tetrahydrate; ethylenediamine / ethanol / 4 h / 20 °C / Inert atmosphere
With
sodium tetrahydroborate; lithium amide; nickel(II) acetate tetrahydrate; ferric nitrate; ethylenediamine;
In
diethyl ether; ethanol;
DOI:10.1021/jo201027u
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium; mercury dichloride / diethyl ether / 0.17 h / 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
1.3: Saturated solution; Inert atmosphere; Cooling with ice
2.1: lithium amide; ferric nitrate / diethyl ether / 1 h / -78 °C / Inert atmosphere
2.2: Inert atmosphere
3.1: sodium tetrahydroborate; nickel(II) acetate tetrahydrate; ethylenediamine / ethanol / 4 h / 20 °C / Inert atmosphere
With
sodium tetrahydroborate; lithium amide; nickel(II) acetate tetrahydrate; magnesium; ferric nitrate; ethylenediamine; mercury dichloride;
In
diethyl ether; ethanol;
DOI:10.1021/jo201027u
