(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Base Information

Chemical Name:(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane
CAS No.:119347-47-6
Molecular Formula:C₁₈H₂₈O₄
Molecular Weight:308.418
Hs Code.:

Synonyms:(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Suppliers and Price of (3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

There total 11 articles about (3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.7%

: 119347-45-4
(3S,4aS,6S,7S,8aS)-3-acetoxyethyl-6,7-dihydroxy-2,2,6-trimethyl-1-methylenedecahydronaphthalene

: 119347-47-6
(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Guidance literature:: With lead(IV) acetate; sodium acetate; In benzene; Ambient temperature;
DOI:10.1016/S0040-4020(01)90097-3

Reference yield: 13.4%

: 119347-46-5,119433-60-2
(3S,4aS,6RS,7RS,8aS)-3-acetoxyethyl-6,7-epoxy-2,2,6-trimethyl-1-methylene-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene

: 119347-47-6
(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

: 119347-45-4
(3S,4aS,6S,7S,8aS)-3-acetoxyethyl-6,7-dihydroxy-2,2,6-trimethyl-1-methylenedecahydronaphthalene

Guidance literature:: With periodic acid; In tetrahydrofuran; diethyl ether; for 0.5h; Ambient temperature;
DOI:10.1016/S0040-4020(01)90097-3

Reference yield:

: 70591-46-7
(S)-5-methoxycarbonylmethyl-6,6-dimethyl-2-cyclohexen-1-one

: 119347-47-6
(3S,5R,6S)-3-acetoxy-5-(2-oxopropyl)-6-formylmethyl-2,2-dimethyl-1-methylenecyclohexane

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) SnCl₄ / 1.) CH₂Cl₂, 20 to 25 deg C, 5 h, 2.) CH₂Cl₂, 48 h, RT; var. solv., time, temp. and cat.: AlCl₃, BF₃*Et₂O

2: 95 percent / NaOMe / methanol / 3 h / Ambient temperature

3: 75 percent / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) RT

4: 78 percent / Li, NH₃ / tetrahydrofuran / 1 h / -23 °C

5: 92 percent / LAH / diethyl ether / 0.5 h / Heating

6: 95 percent / pyridine / Ambient temperature

7: 85 percent / 80percent MCPBA / CHCl₃ / 0 - 5 °C

8: 85.5 percent / HIO₄ / diethyl ether; tetrahydrofuran / 0.5 h / Ambient temperature

With pyridine; lithium aluminium tetrahydride; ammonia; sodium methylate; lithium; periodic acid; 3-chloro-benzenecarboperoxoic acid; tin(IV) chloride; In tetrahydrofuran; methanol; diethyl ether; chloroform;
DOI:10.1016/S0040-4020(01)90097-3