ETHYL 3-HYDROXY-5-PHENYLTHIOPHENE-2-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 3-HYDROXY-5-PHENYLTHIOPHENE-2-CARBOXYLATE
• CAS No.: 2158-86-3
• Molecular Formula: C₁₃H₁₂O₃S
• Molecular Weight: 248.302
• Hs Code.: 2934999090
• Mol file: 2158-86-3.mol

Synonyms:3-hydroxy-5-phenyl-thiophene-2-carboxylic acid ethyl ester;3-Hydroxy-5-phenyl-thiophen-2-carbonsaeure-aethylester;

Chemical Property of ETHYL 3-HYDROXY-5-PHENYLTHIOPHENE-2-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 68 °C(Solv: ethanol (64-17-5))
• Refractive Index: 1.601
• Boiling Point: 397.1°Cat760mmHg
• PKA: 9.42±0.15(Predicted)
• Flash Point: 194°C
• PSA: 74.77000
• Density: 1.26g/cm³
• LogP: 3.29740

Purity/Quality:

99% ^*data from raw suppliers

Ethyl3-hydroxy-5-phenylthiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 3-HYDROXY-5-PHENYLTHIOPHENE-2-CARBOXYLATE

There total 6 articles about ETHYL 3-HYDROXY-5-PHENYLTHIOPHENE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-bis-ethoxycarbonylmethylsulfanyl-3-phenyl-propionic acid ethyl ester (75794-15-9) → 3-Hydroxy-5-phenyl-thiophen-carbonsaeure-(2)-aethylester (2158-86-3)

Guidance literature:

With alkali; In water; Yield given; Heating;

Reference yield:

→ 3-Hydroxy-5-phenyl-thiophen-carbonsaeure-(2)-aethylester (2158-86-3)

Guidance literature:

With ethanol; sodium ethanolate;

Reference yield:

3,3-bis-carboxymethylsulfanyl-3-phenyl-propionic acid ethyl ester (109570-45-8) → 3-Hydroxy-5-phenyl-thiophen-carbonsaeure-(2)-aethylester (2158-86-3)

Guidance literature:

With hydrogenchloride; ethanol; Behandeln des Reaktionsprodukts mit aethanol. Kalilauge;

DOI:10.1111/j.1945-5100.2000.tb01511.x

upstream raw materials:

3,3-bis-carboxymethylsulfanyl-3-phenyl-propionic acid ethyl ester

ethyl 2-sulfanylacetate

phenylpropynoic acid ethyl ester

3,3-bis-ethoxycarbonylmethylsulfanyl-3-phenyl-propionic acid ethyl ester

Downstream raw materials:

3-acetoxy-5-phenyl-thiophene-2-carboxylic acid ethyl ester