(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol

Base Information

• Chemical Name: (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol
• CAS No.: 131755-76-5
• Molecular Formula: C₃₃H₅₂O₇Si
• Molecular Weight: 588.857
• Mol file: 131755-76-5.mol

Synonyms:(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol

Chemical Property of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol

There total 4 articles about (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-3,5-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane (131755-75-4) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol (131755-76-5)

Guidance literature:

With hydrogenchloride; In methanol; for 0.166667h; Ambient temperature;

DOI:10.1016/S0040-4020(01)85585-X

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol (131755-76-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / 2,6-di-t-butylpyridine / CH₂Cl₂ / 48 h

2: 100 percent / 2N HCl / methanol / 0.17 h / Ambient temperature

With hydrogenchloride; 2,6-di-tert-butyl-pyridine; In methanol; dichloromethane;

DOI:10.1016/S0040-4020(01)85585-X

Reference yield:

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester (114811-23-3) → (2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane-3,5-diol (131755-76-5)

Guidance literature:

Multi-step reaction with 3 steps

1: acetalization

2: 100 percent / 2,6-di-t-butylpyridine / CH₂Cl₂ / 48 h

3: 100 percent / 2N HCl / methanol / 0.17 h / Ambient temperature

With hydrogenchloride; 2,6-di-tert-butyl-pyridine; In methanol; dichloromethane;

DOI:10.1016/S0040-4020(01)85585-X

upstream raw materials:

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-3,5-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane

t-butyldimethylsiyl triflate

Benzoic acid (2R,3S,4S,5R,6R,7R)-3,5,6-trihydroxy-7-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonyl ester

Benzoic acid (R)-2-{(4S,5S,6R)-6-[(1R,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-1-methyl-butyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propyl ester

Downstream raw materials:

(2R,3S,4S,5R,6R,7R)-1-Benzoyloxy-6-<(1,1-dimethylethyl)dimethylsilyloxy>-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-(2,4,6-trimethylbenzylidenedioxy)nonane

C₇₅H₁₀₆O₁₂SSi₂

(1EZ,3R,4S,5S,6R,7R,8R)-1-Benzoyloxy-7-<(1,1-dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)dec-1-ene

(3R,4S,5S,6R,7R,8R)-7-<(1,1-Dimethylethyl)dimethylsilyloxy>-8-(4-methoxybenzyloxy)-3,5,7-trimethyl-4,6-(2,4,6-trimethylbenzylidenedioxy)decan-1-ol