Technology Process of 2-(Benzyloxy)-3-hydroxy-6-<<(trifluoromethyl)sulfonyl>oxy>-7,8,9,10-tetrahydrophenanthridine
There total 5 articles about 2-(Benzyloxy)-3-hydroxy-6-<<(trifluoromethyl)sulfonyl>oxy>-7,8,9,10-tetrahydrophenanthridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
acetonitrile;
1.) 0 deg C, 30 min, 2.) r.t., 30 min;
DOI:10.1021/jo00078a046
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 93 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 0 °C
2: 87 percent / PCC, molecular sieves 4 Angstroem / CH2Cl2 / 1 h / Ambient temperature
3: 77 percent / mCPBA / CH2Cl2 / 14 h / Ambient temperature
4: 100 percent / 37percent aq. HCl / methanol / 0.25 h / Heating
5: 50 percent / Et3N / acetonitrile / 1.) 0 deg C, 30 min, 2.) r.t., 30 min
With
hydrogenchloride; lithium aluminium tetrahydride; 4 A molecular sieve; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1021/jo00078a046
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / PCC, molecular sieves 4 Angstroem / CH2Cl2 / 1 h / Ambient temperature
2: 77 percent / mCPBA / CH2Cl2 / 14 h / Ambient temperature
3: 100 percent / 37percent aq. HCl / methanol / 0.25 h / Heating
4: 50 percent / Et3N / acetonitrile / 1.) 0 deg C, 30 min, 2.) r.t., 30 min
With
hydrogenchloride; 4 A molecular sieve; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate;
In
methanol; dichloromethane; acetonitrile;
DOI:10.1021/jo00078a046
