3-methoxy[α-13C]benzyl iodide

Base Information

• Chemical Name: 3-methoxy[α-13C]benzyl iodide
• CAS No.: 741283-61-4
• Molecular Formula: C₈H₉IO
• Molecular Weight: 249.052
• Mol file: 741283-61-4.mol

Synonyms:3-methoxy[α-13C]benzyl iodide

Chemical Property of 3-methoxy[α-13C]benzyl iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methoxy[α-13C]benzyl iodide

There total 3 articles about 3-methoxy[α-13C]benzyl iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-methoxy[α-13C]benzyl alcohol (741283-54-5) → 3-methoxy[α-13C]benzyl iodide (741283-61-4)

Guidance literature:

With phosphorous triiodide; In diethyl ether; at 0 - 20 ℃;

Reference yield:

3-methoxy[carboxy-13C]benzoic acid (741283-53-4) → 3-methoxy[α-13C]benzyl iodide (741283-61-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / lithium aluminium hydride / diethyl ether / 48 h / 20 °C

2: phosphorus triiodide / diethyl ether / 20 °C

With lithium aluminium tetrahydride; phosphorous triiodide; In diethyl ether;

DOI:10.1002/jlcr.1007

Reference yield:

3-methoxybenzo<13C>nitrile (159528-75-3) → 3-methoxy[α-13C]benzyl iodide (741283-61-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / sodium hydroxide / 18 h / Heating

2: 83 percent / lithium aluminium hydride / diethyl ether / 48 h / 20 °C

3: phosphorus triiodide / diethyl ether / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; phosphorous triiodide; In diethyl ether;

DOI:10.1002/jlcr.1007

upstream raw materials:

3-methoxy[α-13C]benzyl alcohol

3-methoxy[carboxy-13C]benzoic acid

3-methoxybenzo<13C>nitrile

Downstream raw materials:

[7,7',9'-13C₃]enterolactone

[7,7',9'-13C₃]enterodiol

3,4-bis-(3'-methoxy-[¹³C]-benzyl)dihydro-2(3H)-furanone