1-bromo-3-chloro-2-nitrobenzene

Base Information

• Chemical Name: 1-bromo-3-chloro-2-nitrobenzene
• CAS No.: 59772-48-4
• Molecular Formula: C₆H₃BrClNO₂
• Molecular Weight: 236.452
• Mol file: 59772-48-4.mol

Synonyms:1-bromo-3-chloro-2-nitrobenzene

Chemical Property of 1-bromo-3-chloro-2-nitrobenzene

Chemical Property:

• Melting Point: 74.4 °C
• Boiling Point: 256.3±20.0 °C(Predicted)
• Density: 1.827±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

95% ^*data from raw suppliers

1-Bromo-3-chloro-2-nitrobenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-bromo-3-chloro-2-nitrobenzene

There total 3 articles about 1-bromo-3-chloro-2-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-bromo-6-chloroaniline (59772-49-5) → 1-bromo-3-chloro-2-nitrobenzene (59772-48-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In 1,2-dichloro-ethane; at 70 ℃; for 2h;

DOI:10.1021/ol8026957

Reference yield:

4-Chloro-3-nitroaniline (635-22-3) → 1-bromo-3-chloro-2-nitrobenzene (59772-48-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; NaOBr / man verwandelt in die Acetylderivate, trennt diese durch fraktionierte Krystallisation aus Alkohol und verseift durch konz.Schwefelsaeure bei 120grad

With sodium hypobromide; acetic acid;

Reference yield:

2-bromo-4-chloro-3-nitro-aniline (861525-56-6) → 1-bromo-3-chloro-2-nitrobenzene (59772-48-4)

Guidance literature:

upstream raw materials:

2-bromo-4-chloro-3-nitro-aniline

4-Chloro-3-nitroaniline

2-bromo-6-chloroaniline

Downstream raw materials:

3-chloro-4-(3'-chloro-2'-nitrophenyl)-N-(TIPS)pyrrole

3-(3'-chloro-2'-nitrophenyl)-N-(TIPS)pyrrole