2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole

Base Information

• Chemical Name: 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole
• CAS No.: 1393812-52-6
• Molecular Formula: C₂₈H₂₂N₄O
• Molecular Weight: 430.509
• Mol file: 1393812-52-6.mol

Synonyms:2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole

Chemical Property of 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole

There total 13 articles about 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-bromo-9-(pyridin-2-yl)-9H-carbazole 3-Br (1352932-32-1) + 3-(3,5-dimethyl-1H-pyrazol-1-yl)phenol (58880-54-9) → 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole (1393812-52-6)

Guidance literature:

With 2-Picolinic acid; potassium phosphate; copper(l) iodide; In dimethyl sulfoxide; at 90 - 100 ℃; for 144h; Inert atmosphere; Sealed tube;

Reference yield: 95.0%

2-bromo-pyridine (109-04-6) + 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9H-carbazole (1393812-51-5) → 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole (1393812-52-6)

Guidance literature:

With 1-methyl-1H-imidazole; copper(l) iodide; potassium carbonate; In toluene; at 120 ℃; for 72h;

Reference yield:

2-[3-(3,5-dimethylpyrazol-1-yl)-phenoxy]-N-(tetrahydropyranyl)carbazole (1393812-50-4) → 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole (1393812-52-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanesulfonic acid / methanol / 2 h / 20 - 50 °C

2: potassium carbonate; copper(l) iodide; 1-methyl-1H-imidazole / toluene / 72 h / 120 °C

With 1-methyl-1H-imidazole; copper(l) iodide; methanesulfonic acid; potassium carbonate; In methanol; toluene;

upstream raw materials:

2-bromo-pyridine

2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9H-carbazole

2-[3-(3,5-dimethylpyrazol-1-yl)-phenoxy]-N-(tetrahydropyranyl)carbazole

1-(3'-bromophenyl)-3,5-dimethyl-1H-pyrazole