(4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide

Base Information

Chemical Name:(4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide
CAS No.:57001-66-8
Molecular Formula:C₁₃H₁₅BrN₂O₂S
Molecular Weight:343.244
Hs Code.:

(4<i>R</i>)-5<i>t</i>-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4<i>r</i>-carboxylic acid methylamide

Synonyms:(4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide

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Technology Process of (4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide

There total 2 articles about (4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57001-62-4
(R)-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4-carboxylic acid methyl ester

: 57001-66-8
(4R)-5t-bromo-2-(4-methoxy-phenyl)-4-methyl-4,5-dihydro-thiazole-4r-carboxylic acid methylamide

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NaOH, aq. MeOH, (ii) oxalyl dichloride, (iii) /BRN= 741851/

2: NBS, AIBN / CCl₄

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane;
DOI:10.1021/ja00850a043