(2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on

Base Information

• Chemical Name: (2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on
• CAS No.: 119215-53-1
• Molecular Formula: C₁₅H₁₉NO₄
• Molecular Weight: 277.32
• Mol file: 119215-53-1.mol

Synonyms:(2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on

Chemical Property of (2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on

There total 1 articles about (2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2R,4S)-3-Benzoyl-4<(benzyloxy)methyl>-2-(tert-butyl)oxazolidin-5-on → (2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on (119215-53-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 24h; under 760 Torr;

DOI:10.1002/hlca.19880710541

Reference yield:

(2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on (119215-53-1) → (2R,4S)-3-Benzoyl-2-(tert-butyl)-5-oxooxazolidin-4-carbonsaeure (119215-54-2)

Guidance literature:

With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; for 12h; Ambient temperature;

DOI:10.1002/hlca.19880710541

Reference yield:

(2R,4S)-3-Benzoyl-2-(tert-butyl)-4-(hydroxymethyl)oxazolidin-5-on (119215-53-1) → (+)-(2R)-3-Benzoyl-2-(tert-butyl)oxazolidin-5-on (119323-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaIO₄, 20 molpercent RuCl₃ / CCl₄; acetonitrile; H₂O / 12 h / Ambient temperature

2: 17 percent / benzoic acid / toluene / 0.17 h / Heating

With ruthenium trichloride; sodium periodate; benzoic acid; In tetrachloromethane; water; toluene; acetonitrile;

DOI:10.1002/hlca.19880710541

Downstream raw materials:

(2R,4S)-3-Benzoyl-2-(tert-butyl)-5-oxooxazolidin-4-carbonsaeure

(2R,4S)-3-benzoyl-2-(tert-butyl)-4-methyl-1,3-oxazolidin-5-one

(+)-(2R)-3-Benzoyl-2-(tert-butyl)oxazolidin-5-on