(S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide

Base Information

• Chemical Name: (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide
• CAS No.: 1313186-38-7
• Molecular Formula: C₁₅H₁₅N₃O₇S
• Molecular Weight: 381.366
• Mol file: 1313186-38-7.mol

Synonyms:(S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide

Chemical Property of (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide

There total 2 articles about (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.2%

2,4-dinitrobenzenesulfonyl chloride (1656-44-6) + L-Phenylalaninol (3182-95-4) → (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide (1313186-38-7)

Guidance literature:

With sodium carbonate; In tetrahydrofuran; at 0 ℃; for 4h;

DOI:10.1002/ejoc.201100358

Reference yield:

(S)-2,4-dinitro-N-(1-oxo-3-phenylpropan-2-yl)benzenesulfonamide → (S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide (1313186-38-7)

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1002/ejoc.201700089

Reference yield:

(S)-N-(1-benzyl-2-hydroxyethyl)-2,4-dinitrophenylsulfonamide (1313186-38-7) → (S)-2,4-dinitro-N-(1-oxo-3-phenylpropan-2-yl)benzenesulfonamide

Guidance literature:

With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide; In dichloromethane; water; at -5 ℃; for 0.5h;

DOI:10.1002/ejoc.201700089

upstream raw materials:

2,4-dinitrobenzenesulfonyl chloride

L-Phenylalaninol

Downstream raw materials:

(S)-2-(1-methylethyl)-1-(2,4-dinitrophenylsulfonyl)aziridine

(S)-N-(1-benzyl-2-methoxyethyl)-2,4-dinitrophenylsulfonamide

(S)-N-(1-benzyl-2-benzyloxyethyl)-2,4-dinitrophenylsulfonamide

(S)-N-(1-benzyl-2-(1-methyloxyethyl)ethyl)-2,4-dinitrophenylsulfonamide