3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole

Base Information

• Chemical Name: 3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole
• CAS No.: 913341-59-0
• Molecular Formula: C₁₃H₁₆N₂
• Molecular Weight: 200.283
• Mol file: 913341-59-0.mol

Synonyms:3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole

Chemical Property of 3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole

There total 1 articles about 3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

5-phenyl-5-methyl-2,4-hexanedione → 3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole (913341-59-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 2h; Heating;

DOI:10.1016/j.jorganchem.2006.06.026

Reference yield: 57.0%

3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole (913341-59-0) + potassium borohydride + thallium(I) nitrate → thallium hydrido-tris[3-(1',1'-dimethylbenzyl)-5-methyl-pyrazol-1-yl]borato

Guidance literature:

In tetrahydrofuran; byproducts: H2; under N2; mixt. of KBH4 and ligand heated gradually with stirring up to 240°C; kept at this temp. for 5 h; cooled to room temp.; disolvedin THF; added to TlNO3 in H2O-CH2Cl2; stirred at room temp. for 1 h; extd. with Et2O; dried (Na2SO4); solvent evapd. in vac.; hexane added; stirred for 1 h; filtered; dried in vac.; additional crop obtained by cooling mother liquor at -18°C; elem. anal.;

DOI:10.1016/j.jorganchem.2006.06.026

Reference yield:

3-(1',1'-dimethylbenzyl)-5-methyl-pyrazole (913341-59-0) → (hydrido-bis[3-methyl-5-(1',1'-dimethylbenzyl)-pyrazol-1-yl]-[3-(1',1'-dimethylbenzyl)-5-methyl-pyrazol-1-yl]borato)trichloro-titanium(IV)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran

2: dichloromethane

In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.jorganchem.2006.06.026