N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

Base Information

Chemical Name:N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine
CAS No.:1449515-71-2
Molecular Formula:C₁₉H₁₈N₆
Molecular Weight:330.392
Hs Code.:

Synonyms:N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

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Chemical Property of N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

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Technology Process of N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

There total 5 articles about N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 607373-83-1
2-chloro-4-methoxy-5-nitro-pyridine

: 1449515-71-2
N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran / 2 h / 20 °C

2: iron; acetic acid / 50 - 80 °C

3: orthoformic acid triethyl ester / 4 h / 100 °C

4: sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 24 h / 100 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; iron; acetic acid; orthoformic acid triethyl ester; sodium t-butanolate; XPhos; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

: 1449516-27-1
C₁₂H₁₃N₃

: 7205-46-1
6-chloro-1-methyl-1H-imidazo[4,5-c]pyridine

: 1449515-71-2
N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; XPhos; In 1,4-dioxane; at 100 ℃; for 24h; Inert atmosphere;

Reference yield:

: 87034-76-2
6-chloro-N⁴-methylpyridine-3,4-diamine

: 1449515-71-2
N-(2-ethyl-4-(pyrimidin-5-yl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridin-6-amine

Guidance literature:: Multi-step reaction with 2 steps

1: orthoformic acid triethyl ester / 4 h / 100 °C

2: sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 24 h / 100 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; orthoformic acid triethyl ester; sodium t-butanolate; XPhos; In 1,4-dioxane;