(2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

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Chemical Name:(2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate
CAS No.:1239920-18-3
Molecular Formula:C₅₆H₇₅N₇O₁₃S
Molecular Weight:1086.32
Hs Code.:

(2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

Synonyms:(2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

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Chemical Property of (2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

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Technology Process of (2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

There total 1 articles about (2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1239920-15-0
C₂₂H₃₆N₄O₉

: 1239920-21-8
C₃₄H₄₁N₃O₅S

: 1239920-18-3
(2Z,4E)-ethyl 5-(2-((S)-2-(4-(benzyloxy)phenyl)-1-((3S,4R)-3-((S)-1-((S)-2-((S)-1-((R)-2-(tert-butoxycarbonylamino)-3-methoxypropanoyl)pyrrolidine-2-carboxamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methyl-2-oxohexanamido)ethyl)thiazol-4-yl)-2,4-dimethylpenta-2,4-dienoate

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In dichloromethane; at 20 ℃; Cooling with ice;
DOI:10.1016/j.tet.2010.05.040