3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

Base Information

Chemical Name:3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline
CAS No.:1026137-17-6
Molecular Formula:C₂₄H₁₉F₇N₆O
Molecular Weight:540.443
Hs Code.:

Synonyms:3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

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Chemical Property of 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

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Technology Process of 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

There total 1 articles about 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026137-16-5
3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-7-fluoroquinolin-2-carbonitrile

: 925-90-6
ethylmagnesium bromide

: 1026137-17-6
3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

Guidance literature:: 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-7-fluoroquinolin-2-carbonitrile; ethylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 0.5h;

With water; ammonium chloride; In tetrahydrofuran;

Reference yield:

: 1026137-17-6
3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline

: 1026137-18-7
C₂₄H₂₁F₇N₆O

Guidance literature:: 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-2-ethylcarbonyl-7-fluoroquinoline; With sodium tetrahydroborate; In ethanol; at 0 ℃; for 0.5h;

With water; ammonium chloride; In ethanol;