(+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)

Base Information

• Chemical Name: (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)
• CAS No.: 85486-81-3
• Molecular Formula: C₁₆H₁₉NO₈
• Molecular Weight: 353.329

Synonyms:(+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)

Chemical Property of (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)

There total 2 articles about (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(+/-)-<3S-<3α(S*),4α>>-1-(2,4-dimethoxybenzyl)-3-(1-acetoxyethyl)-4-ethoxycarbonyl-2-azetidinone-4-carboxylic acid (81902-52-5,87479-86-5) → (+/-)-(R*,S*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid) (85486-81-3)

Guidance literature:

With sodium hydroxide; In pyridine; at 0 ℃; for 20h;

DOI:10.1016/S0040-4020(01)91966-0

Reference yield: 61.0%

(R)-3-((S)-1-Acetoxy-ethyl)-1-(2,4-dimethoxy-benzyl)-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester (80829-71-6,81902-51-4,85550-26-1) → (+/-)-(R*,S*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid) (85486-81-3)

Guidance literature:

With sodium hydroxide; In pyridine;

Reference yield: 100.0%

(+/-)-(R*,S*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid) (85486-81-3) → (+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylic acid (85486-82-4,85761-35-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran;

upstream raw materials:

(+/-)-<3S-<3α(S^*),4α>>-1-(2,4-dimethoxybenzyl)-3-(1-acetoxyethyl)-4-ethoxycarbonyl-2-azetidinone-4-carboxylic acid

(R)-3-((S)-1-Acetoxy-ethyl)-1-(2,4-dimethoxy-benzyl)-4-oxo-azetidine-2,2-dicarboxylic acid diethyl ester

Downstream raw materials:

(+/-)-<1α,4α,5α>-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylic acid

(+/-)-<1α,4α,5α>-t-butyl-7-(2,4-dimethoxybenzyl)-2,6-dioxo-4-methyl-3-oxa-7-azabicyclo<3.2.0>heptane-1-carboxylate

(+/-)-<3α(S^*),4β>-t-butyl-1-(2,4-dimethoxybenzyl)-3-(1-t-butoxycarbonylcarboxyethyl)-2-azetidinone-4-carboxylate

(+/-)-<3α(S^*),4α>-t-butyl-1-(2,4-dimethoxybenzyl)-3-(1-t-butoxycarbonylcarboxyethyl)-2-azetidinone-4-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 85486-81-3 (+/-)-(R^*,S^*)-1-(2,4-dimethoxybenzyl)-3-(1-hydroxyethyl)-2-azetidinone-4,4-bis(carboxylic acid)

Send

Send

Metric Ton KG G Pound L ML

Send

Send