1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole

Base Information

• Chemical Name: 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole
• CAS No.: 346612-71-3
• Molecular Formula: C₂₂H₂₀N₂O₄
• Molecular Weight: 376.412
• Mol file: 346612-71-3.mol

Synonyms:1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole

Chemical Property of 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole

There total 2 articles about 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

isovanillin (621-59-0) + 1,2-diamino-benzene (95-54-5) → 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole (346612-71-3)

Guidance literature:

With zirconia nanopartices incorporated in multi-walled carbon nanotube nanocomposite; In ethanol; at 20 ℃; for 3h; Green chemistry;

DOI:10.1002/aoc.5906

Reference yield: 49.0%

isovanillin (621-59-0) + 1,2-diamino-benzene (95-54-5) → 1-(3-hydroxy-4-methoxybenzyl)-2-(3-hydroxy-4-methoxyphenyl)-1H-1,3-benzimidazole (346612-71-3) + 2-(3-hydroxy-4-methoxyphenyl)-1H-benzimidazole (73008-32-9)

Guidance literature:

With silica gel; In dichloromethane; at 20 ℃;

DOI:10.1039/c3ra22435j

upstream raw materials:

isovanillin

1,2-diamino-benzene