D-Threonine, N-acetyl-

Base Information

Chemical Name:D-Threonine, N-acetyl-
CAS No.:197302-88-8
Molecular Formula:C6H11 N O4
Molecular Weight:161.158
Hs Code.:
DSSTox Substance ID:DTXSID80453757
Nikkaji Number:J307.733K
Wikidata:Q82274985
Mol file:197302-88-8.mol

Synonyms:D-Threonine, N-acetyl-;197302-88-8;D-Threonine, N-acetyl- (9CI);(2R,3S)-2-ACETAMIDO-3-HYDROXYBUTANOIC ACID;n-acetyl-d-threonine;SCHEMBL6026642;DTXSID80453757;EN300-6847278;55024-18-5

Suppliers and Price of D-Threonine, N-acetyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of D-Threonine, N-acetyl-

Chemical Property:

PSA：90.12000
LogP:-0.20320
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:161.06880783
Heavy Atom Count:11
Complexity:168

Purity/Quality:: >95% by HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C(=O)O)NC(=O)C)O
Isomeric SMILES:C[C@@H]([C@H](C(=O)O)NC(=O)C)O

Technology Process of D-Threonine, N-acetyl-

There total 5 articles about D-Threonine, N-acetyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 197232-62-5
N-[(1R,2S)-1-((4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-imidazolidine-1-carbonyl)-2-hydroxy-propyl]-acetamide

: 197302-88-8
N-acetyl-D-threonine

Guidance literature:: With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 0 ℃;
DOI:10.1016/S0040-4039(97)01630-4

Reference yield:

: 176791-96-1
(4S,5R)-1-((2R,3S)-1-Acetyl-3-methyl-aziridine-2-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one

: 197302-88-8
N-acetyl-D-threonine

Guidance literature:: Multi-step reaction with 3 steps

1: CHCl₃ / 48 h / Ambient temperature

2: p-toluenesulfonic acid, water / CH₂Cl₂ / 4 h / Ambient temperature

3: 70 percent / LiOH, H₂O₂ / tetrahydrofuran; H₂O / 0 °C

With lithium hydroxide; water; dihydrogen peroxide; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; chloroform; water;
DOI:10.1016/S0040-4039(97)01630-4

Reference yield:

: 176791-97-2
(4S,5R)-1-((4R,5S)-2,5-Dimethyl-4,5-dihydro-oxazole-4-carbonyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one

: 197302-88-8
N-acetyl-D-threonine

Guidance literature:: Multi-step reaction with 2 steps

1: p-toluenesulfonic acid, water / CH₂Cl₂ / 4 h / Ambient temperature

2: 70 percent / LiOH, H₂O₂ / tetrahydrofuran; H₂O / 0 °C

With lithium hydroxide; water; dihydrogen peroxide; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/S0040-4039(97)01630-4