ETHYL 2-ETHOXY-3-(4-HYDROXYPHENYL)PROPIONATE

Base Information

• Chemical Name: ETHYL 2-ETHOXY-3-(4-HYDROXYPHENYL)PROPIONATE
• CAS No.: 197299-16-4
• Molecular Formula: C13H18O4
• Molecular Weight: 238.284
• Hs Code.: 2918990090
• Mol file: 197299-16-4.mol

Synonyms:2-Ethoxy-3-(4-hydroxy-phenyl)-propionic acid ethyl ester;

Chemical Property of ETHYL 2-ETHOXY-3-(4-HYDROXYPHENYL)PROPIONATE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.515
• Boiling Point: 367.296 °C at 760 mmHg
• PKA: 9.75±0.15(Predicted)
• Flash Point: 134.932 °C
• PSA: 55.76000
• Density: 1.116 g/cm³
• LogP: 1.90290

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-ethoxy-3-(4-hydroxyphenyl)propanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-ETHOXY-3-(4-HYDROXYPHENYL)PROPIONATE

There total 14 articles about ETHYL 2-ETHOXY-3-(4-HYDROXYPHENYL)PROPIONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-(4-benzyloxy-phenyl)-2-ethoxy-acrylic acid ethyl ester (222835-03-2) → ethyl 2-ethoxy-3-(4-hydroxy-phenyl)-propionate (197299-16-4)

Guidance literature:

With palladium on activated carbon; hydrogen; In ethyl acetate;

Reference yield: 100.0%

3-(4-benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester (223126-28-1) → ethyl 2-ethoxy-3-(4-hydroxy-phenyl)-propionate (197299-16-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmcl.2008.01.067

Reference yield: 100.0%

→ ethyl 2-ethoxy-3-(4-hydroxy-phenyl)-propionate (197299-16-4)

Guidance literature:

upstream raw materials:

3-(4-benzyloxy-phenyl)-2-ethoxy-acrylic acid ethyl ester

3-(4-benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester

p-benzyloxybenzaldehyde

4-hydroxy-benzaldehyde

Downstream raw materials:

ethyl 2-ethoxy-3-[4-(2-fluoren-9-ylidene-ethoxy)-phenyl]-propionate

ethyl 2-ethoxy-3-[4-(2-(9H-fluoren-9-yl)ethoxy]phenyl)propionate

3-(4-dimethylthiocarbamoyloxy-phenyl)-2-ethoxy-propionic acid ethyl ester

ethyl 2-ethoxy-3-{[4-(4-isopropoxy-6-methoxyquinoline-3-yl)methyloxy]phenyl}propanoate

Refernces

• 1、 -. "PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS". Page/Page column 12-13. . Retrieved 2010/10/03.
• 2、 -. "PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS". Page/Page column 17-18. . Retrieved 2009/05/30.