Technology Process of 22-(2,4,6-Triphenyl-1-pyridinio)-3,6,9,12,15,18-hexaoxabicyclo<18.3.1>tetracosa-1(24),20,22-trien-24-ol Tetrafluoroborate
There total 6 articles about 22-(2,4,6-Triphenyl-1-pyridinio)-3,6,9,12,15,18-hexaoxabicyclo<18.3.1>tetracosa-1(24),20,22-trien-24-ol Tetrafluoroborate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1) NaOH / 1) H2O, reflux, 2) reflux, 4 h
2: 79 percent / N-bromosuccinimide, azobisisobutyronitrile / CCl4 / 1.5 h / Heating
3: 37 percent / NaH / tetrahydrofuran / 12 h / Heating
4: 61 percent / anhydr. LiI / pyridine / Heating
5: 67 percent / KNO2, concd. HNO3 / H2O / Ambient temperature
6: 93 percent / H2 / Pd/C / methanol / 760 Torr / Ambient temperature
7: 78 percent / AcOH / CH2Cl2 / Ambient temperature
With
sodium hydroxide; N-Bromosuccinimide; potassium nitrite; 2,2'-azobis(isobutyronitrile); hydrogen; nitric acid; sodium hydride; acetic acid; lithium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; pyridine; methanol; tetrachloromethane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 37 percent / NaH / tetrahydrofuran / 12 h / Heating
2: 61 percent / anhydr. LiI / pyridine / Heating
3: 67 percent / KNO2, concd. HNO3 / H2O / Ambient temperature
4: 93 percent / H2 / Pd/C / methanol / 760 Torr / Ambient temperature
5: 78 percent / AcOH / CH2Cl2 / Ambient temperature
With
potassium nitrite; hydrogen; nitric acid; sodium hydride; acetic acid; lithium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; pyridine; methanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 79 percent / N-bromosuccinimide, azobisisobutyronitrile / CCl4 / 1.5 h / Heating
2: 37 percent / NaH / tetrahydrofuran / 12 h / Heating
3: 61 percent / anhydr. LiI / pyridine / Heating
4: 67 percent / KNO2, concd. HNO3 / H2O / Ambient temperature
5: 93 percent / H2 / Pd/C / methanol / 760 Torr / Ambient temperature
6: 78 percent / AcOH / CH2Cl2 / Ambient temperature
With
N-Bromosuccinimide; potassium nitrite; 2,2'-azobis(isobutyronitrile); hydrogen; nitric acid; sodium hydride; acetic acid; lithium iodide;
palladium on activated charcoal;
In
tetrahydrofuran; pyridine; methanol; tetrachloromethane; dichloromethane; water;
