N-Bsmoc-L-valine

Base Information

Chemical Name:N-Bsmoc-L-valine
CAS No.:197245-17-3
Molecular Formula:C₁₅H₁₇NO₆S
Molecular Weight:339.369
Hs Code.:
DSSTox Substance ID:DTXSID70428833
Nikkaji Number:J1.135.225A
Wikidata:Q82241665
Mol file:197245-17-3.mol

Synonyms:N-Bsmoc-L-valine;197245-17-3;(2S)-2-[(1,1-dioxo-1-benzothiophen-2-yl)methoxycarbonylamino]-3-methylbutanoic acid;(((1,1-Dioxidobenzo[b]thiophen-2-yl)methoxy)carbonyl)-L-valine;DTXSID70428833;AKOS024286578;N-[(1-Benzothiophene 1,1-dioxide)-2-ylmethoxycarbonyl]-L-valine

Suppliers and Price of N-Bsmoc-L-valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-BSMOC-L-VALINE 95.00%
1G
$ 692.00

American Custom Chemicals Corporation
N-BSMOC-L-VALINE 95.00%
5MG
$ 497.52

Total 8 raw suppliers

Chemical Property of N-Bsmoc-L-valine

Chemical Property:

Vapor Pressure:2.22E-15mmHg at 25°C
Melting Point:155-156°C
Refractive Index:1.586
Boiling Point:602.8°Cat760mmHg
Flash Point:318.4°C
PSA：121.64000
Density:1.389g/cm³
LogP:2.93540
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:339.07765844
Heavy Atom Count:23
Complexity:604

Purity/Quality:

98%Min ^*data from raw suppliers

N-BSMOC-L-VALINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O
Isomeric SMILES:CC(C)[C@@H](C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O

Technology Process of N-Bsmoc-L-valine

There total 5 articles about N-Bsmoc-L-valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50779-55-0
benzothiophen-2-yllithium

: 197245-17-3
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 4 steps

1: 2.) NaBH₄ / 2.) MeOH

2: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

3: 36.1 g / tetrahydrofuran / -30 - 20 °C

4: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With sodium perborate; sodium tetrahydroborate; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetic acid;
DOI:10.1021/jo982140l

Reference yield:

: 17890-56-1
benzothiophene-2-methanol

: 197245-17-3
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

2: 36.1 g / tetrahydrofuran / -30 - 20 °C

3: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With sodium perborate; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetic acid;
DOI:10.1021/jo982140l

Reference yield:

: 134996-50-2
1,1-dioxobenzo[b]thiophen-2-ylmethanol

: 197245-17-3
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 2 steps

1: 36.1 g / tetrahydrofuran / -30 - 20 °C

2: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;
DOI:10.1021/jo982140l