N-Bsmoc-L-alanine

Base Information

Chemical Name:N-Bsmoc-L-alanine
CAS No.:197245-15-1
Molecular Formula:C₁₃H₁₃NO₆S
Molecular Weight:311.315
Hs Code.:
DSSTox Substance ID:DTXSID00428826
Nikkaji Number:J1.135.224C
Wikidata:Q82241657
Mol file:197245-15-1.mol

Synonyms:N-Bsmoc-L-alanine;197245-15-1;(2S)-2-[(1,1-dioxo-1-benzothiophen-2-yl)methoxycarbonylamino]propanoic acid;DTXSID00428826;AKOS024348903;N-[(1-Benzothiophene 1,1-dioxide)-2-ylmethoxycarbonyl]-L-alanine

Suppliers and Price of N-Bsmoc-L-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-BSMOC-L-ALANINE 95.00%
1G
$ 602.00

American Custom Chemicals Corporation
N-BSMOC-L-ALANINE 95.00%
5MG
$ 495.56

Total 6 raw suppliers

Chemical Property of N-Bsmoc-L-alanine

Chemical Property:

Vapor Pressure:1.24E-15mmHg at 25°C
Melting Point:105-107°C
Refractive Index:1.606
Boiling Point:608oC at 760 mmHg
Flash Point:321.5oC
PSA：121.64000
Density:1.476g/cm3
LogP:2.29930
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:311.04635831
Heavy Atom Count:21
Complexity:562

Purity/Quality:

99% ^*data from raw suppliers

N-BSMOC-L-ALANINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O
Isomeric SMILES:C[C@@H](C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O

Technology Process of N-Bsmoc-L-alanine

There total 5 articles about N-Bsmoc-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50779-55-0
benzothiophen-2-yllithium

: 197245-15-1
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 4 steps

1: 2.) NaBH₄ / 2.) MeOH

2: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

3: 36.1 g / tetrahydrofuran / -30 - 20 °C

4: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With sodium perborate; sodium tetrahydroborate; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetic acid;
DOI:10.1021/jo982140l

Reference yield:

: 17890-56-1
benzothiophene-2-methanol

: 197245-15-1
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

2: 36.1 g / tetrahydrofuran / -30 - 20 °C

3: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With sodium perborate; chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetic acid;
DOI:10.1021/jo982140l

Reference yield:

: 134996-50-2
1,1-dioxobenzo[b]thiophen-2-ylmethanol

: 197245-15-1
Bsmoc-Ala-OH

Guidance literature:: Multi-step reaction with 2 steps

1: 36.1 g / tetrahydrofuran / -30 - 20 °C

2: 1.) Me₃SiCl, 2.) i-Pr₂NEt / 1.) CH₂Cl₂, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h

With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;
DOI:10.1021/jo982140l