N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Base Information

Chemical Name:N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester
CAS No.:620625-81-2
Molecular Formula:C₂₁H₁₉N₃O₃S
Molecular Weight:393.466
Hs Code.:

<i>N</i>-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-<i>b</i>]pyridin-3-yl]-formimidic acid ethyl ester

Synonyms:N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Suppliers and Price of N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

There total 3 articles about N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 122-51-0
orthoformic acid triethyl ester

: 620625-70-9
5-acetyl-3-amino-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carbonitrile

: 620625-81-2
N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Guidance literature:: In acetic anhydride; for 3h; Heating;

Reference yield:

: 121104-38-9
5-acetyl-3-cyano-4-(4-methoxyphenyl)-6-methylpyridine-2(1H)-thione

: 620625-81-2
N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NaOAc*3H₂O / ethanol / 2 h / Heating

2: NaOAc*3H₂O / ethanol / 2 h / Heating

3: 88 percent / acetic anhydride / 3 h / Heating

With sodium acetate; In ethanol; acetic anhydride; 2: Thorpe-Ziegler cyclization;

Reference yield:

: 620625-67-4
5-acetyl-2-cyanomethylsulfanyl-4-(4-methoxy-phenyl)-6-methyl-nicotinonitrile

: 620625-81-2
N-[5-acetyl-2-cyano-4-(4-methoxy-phenyl)-6-methyl-thieno[2,3-b]pyridin-3-yl]-formimidic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NaOAc*3H₂O / ethanol / 2 h / Heating

2: 88 percent / acetic anhydride / 3 h / Heating

With sodium acetate; In ethanol; acetic anhydride; 1: Thorpe-Ziegler cyclization;