Oxepino4,5-cpyridine

Base Information

• Chemical Name: Oxepino4,5-cpyridine
• CAS No.: 264-33-5
• Molecular Formula: C₉H₇NO
• Molecular Weight: 145.161
• Mol file: 264-33-5.mol

Synonyms:Oxepino4,5-cpyridine

Chemical Property of Oxepino4,5-cpyridine

Chemical Property:

• PSA: 22.12000
• LogP: 2.05320

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxepino4,5-cpyridine

There total 2 articles about Oxepino4,5-cpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-methyl-5,10-dihydro-1H-5,10-[2,3]epoxirenopyrido[3,4-d][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione → oxepino[4,5-c]pyridine (264-33-5)

Guidance literature:

2-methyl-5,10-dihydro-1H-5,10-[2,3]epoxirenopyrido[3,4-d][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione; With potassium hydroxide; In isopropyl alcohol; at 40 ℃; for 4h; Inert atmosphere;

With copper(II) choride dihydrate; oxygen; acetic acid; In water; isopropyl alcohol; at 25 ℃; under 0.750075 Torr; pH=5;

DOI:10.1021/jacs.0c02724

Reference yield:

C12H10N4O2 → oxepino[4,5-c]pyridine (264-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: manganese(II) perchlorate hexahydrate; peracetic acid; 2-Picolinic acid; acetic acid / acetonitrile / 2 h / -20 °C / Inert atmosphere

2.1: potassium hydroxide / isopropyl alcohol / 4 h / 40 °C / Inert atmosphere

2.2: 25 °C / 0.75 Torr / pH 5

With 2-Picolinic acid; peracetic acid; manganese(II) perchlorate hexahydrate; acetic acid; potassium hydroxide; In isopropyl alcohol; acetonitrile;

DOI:10.1021/jacs.0c02724

Refernces