Technology Process of 4-amino-3-fluorobenzenesulfonic acid
There total 9 articles about 4-amino-3-fluorobenzenesulfonic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide; hydrogen;
nickel;
In
water;
Ambient temperature;
DOI:10.1002/hlca.19830660108
- Guidance literature:
-
With
1-methyl-pyrrolidin-2-one; aminosulfonic acid;
In
various solvent(s);
at 145 ℃;
for 8h;
DOI:10.1002/hlca.19830660108
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 48percent hydrobromic acid; 2.) NaNO2; 3.) copper powder / 1.) water, 0 deg C, 40 min; 2.) water, 30 min; 3.) 15 min
2: 1.) iron powder, NH4Cl; 2.) Bechamp-suspension / 1.) water, reflux, 30 min; 2.) reflux, 300 min
3: 1.) 100percent sulfuric acid; 2.) fuming sulfuric acid / 1.) 70 deg C, 20 min; 2.) 90 deg C, 240 min
4: 65.4 percent / hydrogen, 4percent NaOH / Raney-nickel / H2O / Ambient temperature
With
sodium hydroxide; Bechamp-suspension; sulfuric acid; hydrogen bromide; hydrogen; iron; copper; ammonium chloride; sodium nitrite;
nickel;
In
water;
DOI:10.1002/hlca.19830660108
