(3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

Base Information

Chemical Name:(3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate
CAS No.:1210017-49-4
Molecular Formula:C₇H₈O₃S*C₁₁H₁₁F₃N₂O
Molecular Weight:416.421
Hs Code.:

Synonyms:(3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

Suppliers and Price of (3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

There total 1 articles about (3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: (4R,5R)-1-allyl-5-nitro-4-(2,4,5-trifluorophenyl)piperidin-2-one

: 104-15-4
toluene-4-sulfonic acid

: 1210017-49-4
(3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

Guidance literature:: (4R,5R)-1-allyl-5-nitro-4-(2,4,5-trifluorophenyl)piperidin-2-one; With rhodium(III) chloride; In isopropyl alcohol; at 90 - 95 ℃; for 17h; Inert atmosphere;

With hydrogen; In methanol; isopropyl alcohol; at 40 ℃; for 5h; under 5414.51 Torr;

toluene-4-sulfonic acid; In water; isopropyl alcohol; at 20 - 60 ℃;
DOI:10.1021/jo902573q

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1210017-49-4
(3R,4R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-ylammonium toluene-4-sulfonate

: 888321-35-5
[(R)-6-oxo-4-(2,4,5-trifluorophenyl)piperidin-3-yl]carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; water; at 20 ℃; for 15.5h; optical yield given as %ee; Large scale reaction;
DOI:10.1021/jo902573q