9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Base Information

Chemical Name:9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one
CAS No.:909555-40-4
Molecular Formula:C₂₂H₂₁ClO₂
Molecular Weight:352.861
Hs Code.:

Synonyms:9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Suppliers and Price of 9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

There total 5 articles about 9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-chloro-benzyl)-5-methoxy-2-(3-oxo-pentyl)-indan-1-one

: 909555-40-4
9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Guidance literature:: With hydrogenchloride; acetic acid; at 100 ℃; for 2h;
DOI:10.1021/jm060516e

Reference yield:

: 851107-66-9
2-(4-chlorobenzyl)-5-methoxy-1-indanone

: 909555-40-4
9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol / 21.5 h / 65 °C

2: HOAc; aq. HCl / 2 h / 100 °C

With hydrogenchloride; sodium methylate; acetic acid; In methanol; 2: Robinson annulation;
DOI:10.1021/jm060516e

Reference yield:

: 2-(4-chlorobenzylidene)-5-methoxy-1-indanone

: 909555-40-4
9a-(4-chlorobenzyl)-7-methoxy-4-methyl-1,2,8,9,9a-tetrahydro-3H-fluoren-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / selenium; sodium borohydride / tetrahydrofuran / 2 h / 50 °C

2: NaOMe / methanol / 21.5 h / 65 °C

3: HOAc; aq. HCl / 2 h / 100 °C

With hydrogenchloride; selenium; sodium tetrahydroborate; sodium methylate; acetic acid; In tetrahydrofuran; methanol; 3: Robinson annulation;
DOI:10.1021/jm060516e